Ontology highlight
ABSTRACT:
SUBMITTER: Wawrzyniak R
PROVIDER: S-EPMC6015025 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Wawrzyniak Renata R Kosnowska Anna A Macioszek Szymon S Bartoszewski Rafał R Jan Markuszewski Michał M
Scientific reports 20180622 1
Plasma untargeted metabolomics is a common method for evaluation of the mechanisms underlying human pathologies and identification of novel biomarkers. The plasma proteins provide the environment for transport of hydrophobic metabolites. The current sample preparation protocol relies on the immediate precipitation of proteins and thus leads to co-precipitation of a significant fraction of hydrophobic metabolites. Here we present a new simple procedure that overcomes the co-precipitation problem ...[more]