Ontology highlight
ABSTRACT:
SUBMITTER: Xu C
PROVIDER: S-EPMC6015052 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Nature communications 20180622 1
Endothelial cells (ECs) contribute to haematopoietic stem cell (HSC) maintenance in bone marrow, but the differential contributions of EC subtypes remain unknown, owing to the lack of methods to separate with high purity arterial endothelial cells (AECs) from sinusoidal endothelial cells (SECs). Here we show that the combination of podoplanin (PDPN) and Sca-1 expression distinguishes AECs (CD45<sup>-</sup> Ter119<sup>-</sup> Sca-1<sup>bright</sup> PDPN<sup>-</sup>) from SECs (CD45<sup>-</sup> Te ...[more]