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Prognostic Significance of Infarct Size and Location: The Case of Insular Stroke.


ABSTRACT: The prognostic relevance of strokes in different locations is debated. For example, insular strokes have been associated with increased mortality, but this association could reflect their greater severity. In two independent cohorts of patients with supratentorial ischemic stroke (n?=?90 and 105), we studied the prognostic consequences of lesion size and location using voxel-based lesion-symptom mapping before and after volume control, which better accounts for total lesion volume. Strokes affecting the insula were larger than non-insular strokes (28 vs 2cc and 25 vs 3cc, p?

SUBMITTER: Laredo C 

PROVIDER: S-EPMC6015086 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

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Prognostic Significance of Infarct Size and Location: The Case of Insular Stroke.

Laredo Carlos C   Zhao Yashu Y   Rudilosso Salvatore S   Renú Arturo A   Pariente José Carlos JC   Chamorro Ángel Á   Urra Xabier X  

Scientific reports 20180622 1


The prognostic relevance of strokes in different locations is debated. For example, insular strokes have been associated with increased mortality, but this association could reflect their greater severity. In two independent cohorts of patients with supratentorial ischemic stroke (n = 90 and 105), we studied the prognostic consequences of lesion size and location using voxel-based lesion-symptom mapping before and after volume control, which better accounts for total lesion volume. Strokes affec  ...[more]

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