Ontology highlight
ABSTRACT:
SUBMITTER: Shetty S
PROVIDER: S-EPMC6016742 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Shetty Shishir S Weston Christopher J CJ Oo Ye H YH Westerlund Nina N Stamataki Zania Z Youster Janine J Hubscher Stefan G SG Salmi Marko M Jalkanen Sirpa S Lalor Patricia F PF Adams David H DH
Journal of immunology (Baltimore, Md. : 1950) 20110302 7
The common lymphatic endothelial and vascular endothelial receptor (CLEVER-1; also known as FEEL-1 and stabilin-1) is a recycling and intracellular trafficking receptor with multifunctional properties. In this study, we demonstrate increased endothelial expression of CLEVER-1/stabilin-1 at sites of leukocyte recruitment to the inflamed human liver including sinusoids, septal vessels, and lymphoid follicles in inflammatory liver disease and tumor-associated vessels in hepatocellular carcinoma. We ...[more]