Ontology highlight
ABSTRACT:
SUBMITTER: Rodygin KS
PROVIDER: S-EPMC6017323 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Rodygin Konstantin S KS Bogachenkov Alexander S AS Ananikov Valentine P VP
Molecules (Basel, Switzerland) 20180313 3
We developed a simple and efficient strategy to access <i>N</i>-vinyl secondary amines of various naturally occurring materials using readily available solid acetylene reagents (calcium carbide, KF, and KOH). Pyrrole, pyrazole, indoles, carbazoles, and diarylamines were successfully vinylated in good yields. Cross-linked and linear polymers were synthesized from <i>N</i>-vinyl carbazoles through free radical and cationic polymerization. Post-modification of olanzapine (an antipsychotic drug subs ...[more]