A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun.
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ABSTRACT:
SUBMITTER: Qi JJ
PROVIDER: S-EPMC6017501 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
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A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun.
Qi Jing-Jing JJ Yan Yong-Ming YM Cheng Li-Zhi LZ Liu Bao-Hua BH Qin Fu-Ying FY Cheng Yong-Xian YX
Molecules (Basel, Switzerland) 20180203 2
A novel flavonoid glucoside, ruthenicunoid A (<b>1</b>), together with eight known substances, were isolated from the fruits of <i>Lycium ruthenicun</i> Murr. Their structures were elucidated by extensive spectroscopic data and chemical methods. Especially, the absolute configuration of glucose residue in <b>1</b> was assigned by acid hydrolysis followed by derivatization and GC analysis. Biological evaluation towards Sirtuin 1 (SIRT1) found that compounds <b>1</b> and <b>2</b> exhibit inhibitor ...[more]
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