Ontology highlight
ABSTRACT:
SUBMITTER: Szydlarska J
PROVIDER: S-EPMC6017619 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Szydlarska Joanna J Weiss Christine C Marycz Krzysztof K
Molecules (Basel, Switzerland) 20180130 2
Methyl-β-cyclodextrin (MβCD) is a cyclic oligosaccharide, commonly used as a pharmacological agent to deplete membrane cholesterol. In this study, we examined the effect of MβCD on adipose-derived mesenchymal stromal cells (ASCs) isolated form healthy horses (ASC<sub>CTRL</sub>) and from horses suffering from metabolic syndrome (ASC<sub>EMS</sub>). We investigated the changes in the mRNA levels of the glucose transporter 4 (GLUT4) and found that MβCD application may lead to a significant improve ...[more]