Ontology highlight
ABSTRACT:
SUBMITTER: Zheng Q
PROVIDER: S-EPMC6020470 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Zheng Qi Q Bartow-McKenney Casey C Meisel Jacquelyn S JS Grice Elizabeth A EA
Genome biology 20180627 1
Culture-independent analysis of microbial communities frequently relies on amplification and sequencing of the prokaryotic 16S ribosomal RNA gene. Typical analysis pipelines group sequences into operational taxonomic units (OTUs) to infer taxonomic and phylogenetic relationships. Here, we present HmmUFOtu, a novel tool for processing microbiome amplicon sequencing data, which performs rapid per-read phylogenetic placement, followed by phylogenetically informed clustering into OTUs and taxonomy a ...[more]