A taxonomic signature of obesity in a large study of American adults.
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ABSTRACT:
SUBMITTER: Peters BA
PROVIDER: S-EPMC6021409 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Publications
A taxonomic signature of obesity in a large study of American adults.
Peters Brandilyn A BA Shapiro Jean A JA Church Timothy R TR Miller George G Trinh-Shevrin Chau C Yuen Elizabeth E Friedlander Charles C Hayes Richard B RB Ahn Jiyoung J
Scientific reports 20180627 1
Animal models suggest that gut microbiota contribute to obesity; however, a consistent taxonomic signature of obesity has yet to be identified in humans. We examined whether a taxonomic signature of obesity is present across two independent study populations. We assessed gut microbiome from stool for 599 adults, by 16S rRNA gene sequencing. We compared gut microbiome diversity, overall composition, and individual taxon abundance for obese (BMI ≥ 30 kg/m<sup>2</sup>), overweight (25 ≤ BMI < 30), ...[more]
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