Molecular Characterization of qnrVC Genes and Their Novel Alleles in Vibrio spp. Isolated from Food Products in China.
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ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC6021619 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Publications
Molecular Characterization of <i>qnrVC</i> Genes and Their Novel Alleles in Vibrio spp. Isolated from Food Products in China.
Zhang Yanyan Y Zheng Zhiwei Z Chan Edward Wai-Chi EW Dong Ning N Xia Xiaodong X Chen Sheng S
Antimicrobial agents and chemotherapy 20180626 7
This study reports the prevalences of <i>qnrVC</i> genes in 74 ciprofloxacin-resistant <i>Vibrio</i> sp. isolates. Two novel functional <i>qnrVC</i> alleles, <i>qnrVC8</i> and <i>qnrVC9</i>, sharing 98% and 99% nucleotide similarity with <i>qnrVC6</i> and <i>qnrVC7</i>, respectively, were identified. Our findings suggested that carriage of <i>qnrVC</i> alleles, together with target mutations in <i>gyrA</i> and <i>parC</i> genes, may contribute to the development of fluoroquinolone resistance in ...[more]
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