Ontology highlight
ABSTRACT:
SUBMITTER: Chen RW
PROVIDER: S-EPMC6022297 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Chen Robert W RW Palmer Joycelynne M JM Tomassetti Sarah S Popplewell Leslie L LL Alluin Jessica J Chomchan Pritsana P Nademanee Auayporn P AP Siddiqi Tanya T Tsai Ni-Chun NC Chen Lu L Zuo Fay F Abary Rosemarie R Cai Ji-Lian JL Herrera Alex F AF Rossi John J JJ Rosen Steven T ST Forman Stephen J SJ Kwak Larry W LW Holmberg Leona A LA
Journal of hematology & oncology 20180628 1
<h4>Background</h4>Mantle cell lymphoma (MCL) is an aggressive and incurable lymphoma. Standard of care for younger patients with MCL is induction chemotherapy followed by autologous stem cell transplantation (auto-HCT). Rituximab maintenance after auto-HCT has been shown to improve progression-free survival (PFS) and overall survival (OS) in MCL. Bortezomib maintenance therapy has also been shown to be tolerable and feasible in this setting. However, the combination of bortezomib and rituximab ...[more]