Applications of Synthetic Organic Tetrasulfides as H2S Donors.
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ABSTRACT:
SUBMITTER: Cerda MM
PROVIDER: S-EPMC6022400 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Publications
Applications of Synthetic Organic Tetrasulfides as H<sub>2</sub>S Donors.
Cerda Matthew M MM Hammers Matthew D MD Earp Mary S MS Zakharov Lev N LN Pluth Michael D MD
Organic letters 20170425 9
In an effort to expand the availability of simple polysulfides for H<sub>2</sub>S donation, we report here the synthesis and H<sub>2</sub>S release profiles of bis(aryl) and bis(alkyl) tetrasulfides. The tetrasulfide donors release H<sub>2</sub>S in a first-order dependence on reduced glutathione (GSH) and release more H<sub>2</sub>S than the commonly used trisulfide DATS. ...[more]
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