Triclosan and triclocarban exposure, infectious disease symptoms and antibiotic prescription in infants-A community-based randomized intervention.

ABSTRACT:

Background

Triclosan and triclocarban (TCs) are broad-spectrum antimicrobials that, until recently, were found in a wide variety of household and personal wash products. Popular with consumers, TCs have not been shown to protect against infectious diseases.

Objectives

To determine whether use of TC-containing wash products reduces incidence of infection in children less than one year of age.

Methods

Starting in 2011, we nested a randomized intervention of wash products with and without TCs within a multiethnic birth cohort. Maternal reports of infectious disease symptoms and antibiotic use were collected weekly by automated survey; household visits occurred every four months. Antibiotic prescriptions were identified by medical chart review. Urinary triclosan levels we

SUBMITTER: Ley C 

PROVIDER: S-EPMC6023107 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature