An active retrotransposon in Candida albicans.
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ABSTRACT:
SUBMITTER: Holton NJ
PROVIDER: S-EPMC60234 | biostudies-literature | 2001 Oct
REPOSITORIES: biostudies-literature
Publications
An active retrotransposon in Candida albicans.
Holton N J NJ Goodwin T J TJ Butler M I MI Poulter R T RT
Nucleic acids research 20011001 19
Tca2 is a Ty1/copia-type retrotransposon from the pathogenic yeast Candida albicans. It was originally identified as an abundant, linear, extrachromosomal, double-stranded DNA molecule. Here we show that Tca2 is widespread in C.albicans, but that the abundance of extrachromosomal Tca2 DNA varies greatly among different strains and is strongly dependent on the growth temperature. The relative levels of Tca2 RNA vary in a similar pattern to the extrachromosomal DNA, raising the possibility that th ...[more]
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