Ontology highlight
ABSTRACT:
SUBMITTER: Zhou Q
PROVIDER: S-EPMC6023938 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Zhou Qin Q Kunder Nikesh N De la Paz José Alberto JA Lasley Alexandra E AE Bhat Vandita D VD Morcos Faruck F Campbell Zachary T ZT
Nature communications 20180628 1
RNA-protein interactions permeate biology. Transcription, translation, and splicing all hinge on the recognition of structured RNA elements by RNA-binding proteins. Models of RNA-protein interactions are generally limited to short linear motifs and structures because of the vast sequence sampling required to access longer elements. Here, we develop an integrated approach that calculates global pairwise interaction scores from in vitro selection and high-throughput sequencing. We examine four RNA ...[more]