Ontology highlight
ABSTRACT:
SUBMITTER: Barnet MB
PROVIDER: S-EPMC6024943 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Barnet Megan B MB Cooper Wendy A WA Boyer Michael J MJ Kao Steven S
Journal of clinical medicine 20180614 6
Immune checkpoint inhibitors have shown efficacy in the treatment of non-small cell lung cancer (NSCLC) in the adjuvant, first- and subsequent-line settings. In metastatic disease, they provide hope of durable response where “best-case” scenario has long been inadequate. This progress has highlighted the immunogenic nature of NSCLC and invigorated research into immunotherapy in the field. In this review we consider the foundations of immunotherapy in NSCLC, canvass the current resear ...[more]