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Age-dependent difference in impact of fertility preserving surgery on disease-specific survival in women with stage I borderline ovarian tumors.


ABSTRACT:

Background

This study was to determine age-specific impact of fertility preserving surgery on disease-specific survival in women with stage I borderline ovarian tumors (BOTs). Patients diagnosed during 1988-2000 were selected from The Surveillance, Epidemiology, and End Results (SEER) database. The age-specific impact of fertility preserving surgery and other risk factors were analyzed in patients with stage I BOTs using Cox proportion hazard regression models. Data from our hospital were collected during 1996-2017 to determine the prevalence of patients who had undergone fertility preserving surgery.

Results

Of a total 6295 patients in the SEER database, this study selected 2946 patients with stage T1 BOTs who underwent fertility preserving or radical surgery. Their median age at diagnosis was 45.0 years and the median follow-up time was 200 months. Fertility preserving surgery was performed in 1000/1751 (57.1%) patients ConclusionFertility preserving surgery is safe for women

SUBMITTER: Sun H 

PROVIDER: S-EPMC6025735 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

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Publications

Age-dependent difference in impact of fertility preserving surgery on disease-specific survival in women with stage I borderline ovarian tumors.

Sun Haiyan H   Chen Xi X   Zhu Tao T   Liu Nanfang N   Yu Aijun A   Wang Shihua S  

Journal of ovarian research 20180629 1


<h4>Background</h4>This study was to determine age-specific impact of fertility preserving surgery on disease-specific survival in women with stage I borderline ovarian tumors (BOTs). Patients diagnosed during 1988-2000 were selected from The Surveillance, Epidemiology, and End Results (SEER) database. The age-specific impact of fertility preserving surgery and other risk factors were analyzed in patients with stage I BOTs using Cox proportion hazard regression models. Data from our hospital wer  ...[more]

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