Ontology highlight
ABSTRACT:
SUBMITTER: O'Donnell VB
PROVIDER: S-EPMC6026006 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
The Journal of clinical investigation 20180423 7
Phospholipids comprise a large body of lipids that define cells and organelles by forming membrane structures. Importantly, their complex metabolism represents a highly controlled cellular signaling network that is essential for mounting an effective innate immune response. Phospholipids in innate cells are subject to dynamic regulation by enzymes, whose activities are highly responsive to activation status. Along with their metabolic products, they regulate multiple aspects of innate immune cel ...[more]