Human and Microbial Proteins From Corpora Amylacea of Alzheimer's Disease.
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ABSTRACT:
SUBMITTER: Pisa D
PROVIDER: S-EPMC6026157 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Publications
Human and Microbial Proteins From Corpora Amylacea of Alzheimer's Disease.
Pisa Diana D Alonso Ruth R Marina Ana Isabel AI Rábano Alberto A Carrasco Luis L
Scientific reports 20180629 1
Corpora amylacea (CA) are spherical bodies mainly composed of polyglucans and, to a lesser extent, proteins. They are abundant in brains from patients with neurodegenerative diseases, particularly Alzheimer's disease. Although CA were discovered many years ago, their precise origin and function remain obscure. CA from the insular cortex of two Alzheimer's patients were purified and the protein composition was assessed by proteomic analysis. A number of microbial proteins were identified and fung ...[more]
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