Correlations between SIRT1 gene polymorphisms and diabetic kidney disease.
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ABSTRACT:
SUBMITTER: Yue XG
PROVIDER: S-EPMC6030294 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
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Correlations between SIRT1 gene polymorphisms and diabetic kidney disease.
Yue Xin-Ge XG Yang Zai-Gang ZG Zhang Yue Y Qin Gui-Jun GJ Liu Fei F
Royal Society open science 20180613 6
To investigate the correlations between SIRT1 gene polymorphisms and diabetic kidney disease (DKD). There were 150 patients with DKD in the observation group (urinary albumin excretion rate (UAER) ≥ 300 mg 24 h<sup>-1</sup>), and 160 patients with a more than 10 year history of type 2 diabetes but without retinopathy and DKD (UAER < 30 mg 24 h<sup>-1</sup>) in the control group. Genotypes of three tagged single-nucleotide polymorphism loci (rs3818292, rs4746720 and rs10823108) in the SIRT1 gene ...[more]
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