Ontology highlight
ABSTRACT:
SUBMITTER: Xu Y
PROVIDER: S-EPMC6031032 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Xu Youjun Y Wang Shiwei S Hu Qiwan Q Gao Shuaishi S Ma Xiaomin X Zhang Weilin W Shen Yihang Y Chen Fangjin F Lai Luhua L Pei Jianfeng J
Nucleic acids research 20180701 W1
CavityPlus is a web server that offers protein cavity detection and various functional analyses. Using protein three-dimensional structural information as the input, CavityPlus applies CAVITY to detect potential binding sites on the surface of a given protein structure and rank them based on ligandability and druggability scores. These potential binding sites can be further analysed using three submodules, CavPharmer, CorrSite, and CovCys. CavPharmer uses a receptor-based pharmacophore modelling ...[more]