Dataset Information

Design and methodology of the Shanghai child and adolescent large-scale eye study (SCALE).

ABSTRACT:

Importance

Nearly half of children suffering vision impairment reside in China with myopia accounting for the vast majority.

Background

To describe the design and methodology of the Shanghai Child and Adolescent Large-scale Eye Study (SCALE).

Design

The SCALE was a city wide, school-based, prospective survey.

Participants

Children and adolescents aged 4-14 years from kindergarten (middle and senior), primary schools and junior high schools of all 17 districts and counties of the city of Shanghai, China were examined in 2012-2013.

Methods

Each enrolled child underwent vision assessment (distance visual acuity; uncorrected and with corrective device if worn) and their parent/carer completed a questionnaire designed to elicit risk factors associated with myopia. Additionally, non-cycloplegic autorefraction and ocular axial length was measured in a subset of the larger sample.

Main outcome measures

Prevalence and the associated factors of vision impairment, myopia and high myopia in Shanghai.

Results

In 2012-2013, a total of 910 245 of the eligible 1 196 763 children and adolescents identified from census (76%, mean age 9.0 ± 2.7 years [4-14 years]) were enrolled with visual acuity screened in the city of Shanghai. Of these, 610 952 children (67% of the entire sample) underwent non-cycloplegic autorefraction and 219 188 (24% of the entire sample) had both non-cycloplegic autorefraction and axial length measurements.

Conclusions and relevance

The study results will provide insights on the burden of vision impairment, myopia and high myopia in children and adolescents in a metropolitan area of China, and contribute to the policies and strategies to address and limit the burden.

SUBMITTER: He X

PROVIDER: S-EPMC6032906 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Design and methodology of the Shanghai child and adolescent large-scale eye study (SCALE).

He Xiangui X Zhao Rong R Sankaridurg Padmaja P Zhu Jianfeng J Naduvilath Thomas T Ma Yingyan Y Lu Lina L Lv Minzhi M Smith Earl L EL Resnikoff Serge S Naidoo Kovin K Zou Haidong H Xu Xun X

Clinical & experimental ophthalmology 20171027 4

<h4>Importance</h4>Nearly half of children suffering vision impairment reside in China with myopia accounting for the vast majority.<h4>Background</h4>To describe the design and methodology of the Shanghai Child and Adolescent Large-scale Eye Study (SCALE).<h4>Design</h4>The SCALE was a city wide, school-based, prospective survey.<h4>Participants</h4>Children and adolescents aged 4-14 years from kindergarten (middle and senior), primary schools and junior high schools of all 17 districts and cou ...[more]

PMID: 28898521

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Project description:ObjectiveTo present the design, methods, and rationale of the Child/Adolescent Anxiety Multimodal Study (CAMS), a recently completed federally-funded, multi-site, randomized placebo-controlled trial that examined the relative efficacy of cognitive-behavior therapy (CBT), sertraline (SRT), and their combination (COMB) against pill placebo (PBO) for the treatment of separation anxiety disorder (SAD), generalized anxiety disorder (GAD) and social phobia (SoP) in children and adolescents.MethodsFollowing a brief review of the acute outcomes of the CAMS trial, as well as the psychosocial and pharmacologic treatment literature for pediatric anxiety disorders, the design and methods of the CAMS trial are described.ResultsCAMS was a six-year, six-site, randomized controlled trial. Four hundred eighty-eight (N = 488) children and adolescents (ages 7-17 years) with DSM-IV-TR diagnoses of SAD, GAD, or SoP were randomly assigned to one of four treatment conditions: CBT, SRT, COMB, or PBO. Assessments of anxiety symptoms, safety, and functional outcomes, as well as putative mediators and moderators of treatment response were completed in a multi-measure, multi-informant fashion. Manual-based therapies, trained clinicians and independent evaluators were used to ensure treatment and assessment fidelity. A multi-layered administrative structure with representation from all sites facilitated cross-site coordination of the entire trial, study protocols and quality assurance.ConclusionsCAMS offers a model for clinical trials methods applicable to psychosocial and psychopharmacological comparative treatment trials by using state-of-the-art methods and rigorous cross-site quality controls. CAMS also provided a large-scale examination of the relative and combined efficacy and safety of the best evidenced-based psychosocial (CBT) and pharmacologic (SSRI) treatments to date for the most commonly occurring pediatric anxiety disorders. Primary and secondary results of CAMS will hold important implications for informing practice-relevant decisions regarding the initial treatment of youth with anxiety disorders.Trial registrationClinicalTrials.gov NCT00052078.

Dataset Information

Design and methodology of the Shanghai child and adolescent large-scale eye study (SCALE).

Importance

Background

Design

Participants

Methods

Main outcome measures

Results

Conclusions and relevance

Publications

Design and methodology of the Shanghai child and adolescent large-scale eye study (SCALE).

Similar Datasets

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