Ontology highlight
ABSTRACT:
SUBMITTER: Smirnov MS
PROVIDER: S-EPMC6033424 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Smirnov Michael S MS Garrett Tavita R TR Yasuda Ryohei R
PloS one 20180705 7
Synaptic plasticity, the cellular basis for learning and memory, is mediated by a complex biochemical network of signaling proteins. These proteins are compartmentalized in dendritic spines, the tiny, bulbous, post-synaptic structures found on neuronal dendrites. The ability to screen a high number of molecular targets for their effect on dendritic spine structural plasticity will require a high-throughput imaging system capable of stimulating and monitoring hundreds of dendritic spines in vario ...[more]