PASI: A novel pathway method to identify delicate group effects.
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ABSTRACT:
SUBMITTER: Jaakkola MK
PROVIDER: S-EPMC6033442 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
PASI: A novel pathway method to identify delicate group effects.
Jaakkola Maria K MK McGlinchey Aidan J AJ Klén Riku R Elo Laura L LL
PloS one 20180705 7
Pathway analysis is a common approach in diverse biomedical studies, yet the currently-available pathway tools do not typically support the increasingly popular personalized analyses. Another weakness of the currently-available pathway methods is their inability to handle challenging data with only modest group-based effects compared to natural individual variation. In an effort to address these issues, this study presents a novel pathway method PASI (Pathway Analysis for Sample-level Informatio ...[more]
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