Controlled efficacy trial confirming toltrazuril resistance in a field isolate of ovine Eimeria spp.

ABSTRACT:

Background

Coccidiosis due to Eimeria spp. infections in lambs causes increased mortality and substantial production losses, and anticoccidials are important for control of the infection. Anticoccidial resistance has been reported in poultry and swine, and we recently described reduced toltrazuril efficacy in ovine Eimeria spp. in some Norwegian sheep farms using a newly developed faecal oocyst count reduction test (FOCRT). The aim of the present study was to use a controlled efficacy trial to assess the efficacy of toltrazuril against a field isolate suspected of being resistant.

Methods

Twenty lambs, 17-22 days old and raised protected against exposure to coccidia, were infected with a field isolate of 100,000 Eimeria spp. oocysts. This isolate was obtained from a farm wit

SUBMITTER: Odden A 

PROVIDER: S-EPMC6034276 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature