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Evaluation of 153 Asymptomatic Subjects Using the Anopress Portable Anal Manometry Device.


ABSTRACT:

Background/aims

The Anopress device is a new portable manometry system. The aim of this study is to formulate normative data using this new device by recording the anorectal function of asymptomatic subjects. Patient comfort was also assessed.

Methods

Anorectal function was assessed in asymptomatic volunteers using the Anopress. All volunteers were examined in a standardized way in accordance with the study protocol. Normative values for the Anopress were obtained from the recorded data and patient comfort was assessed using a visual analogue scale.

Results

We recruited 153 healthy volunteers. Eighty were female (23 parous; median age 39.5 [interquartile range {IQR}, 28.75-53.00]) and 73 were male (median age 40.5 [IQR, 29.00-52.25]). For the female cohort, the following normal range (2.5-97.5 percentile) values were recorded across the whole anal canal: resting pressure 40.0-103.0 mmHg; squeeze increment 35.0-140.6 mmHg; endurance 1.3-9.0 seconds; involuntary squeeze 41.1-120.8 mmHg; and strain pressure 22.1-77.9 mmHg. Similarly, the following male normal range (2.5-97.5 percentile) values were recorded across the whole anal canal: resting pressure 38.3-99.6 mmHg; squeeze increment 42.5-154.8 mmHg; involuntary squeeze 40.0-123.6 mmHg; endurance 2.0-10.0 seconds; and strain pressure 11.0-72.1 mmHg. The median visual analogue scale scores for discomfort during the measurement was 0.0 (IQR, 0.00-0.00).

Conclusions

Normative values for the Anopress device have been calculated by this study. The Anopress appears to be a safe and well tolerated way of measuring pressures from the entire anal canal. Further comparisons with other standard and commonly used manometry tests are, however, required to verify its reliability.

SUBMITTER: Leo CA 

PROVIDER: S-EPMC6034678 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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Evaluation of 153 Asymptomatic Subjects Using the Anopress Portable Anal Manometry Device.

Leo Cosimo Alex CA   Cavazzoni Emanuel E   Thomas Gregory P GP   Hodgkison Jonathan J   Murphy Jamie J   Vaizey Carolynne J CJ  

Journal of neurogastroenterology and motility 20180701 3


<h4>Background/aims</h4>The Anopress device is a new portable manometry system. The aim of this study is to formulate normative data using this new device by recording the anorectal function of asymptomatic subjects. Patient comfort was also assessed.<h4>Methods</h4>Anorectal function was assessed in asymptomatic volunteers using the Anopress. All volunteers were examined in a standardized way in accordance with the study protocol. Normative values for the Anopress were obtained from the recorde  ...[more]

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