Ontology highlight
ABSTRACT:
SUBMITTER: Beas BS
PROVIDER: S-EPMC6035776 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Nature neuroscience 20180618 7
The paraventricular nucleus of the thalamus (PVT) is increasingly being recognized as a critical node linking stress detection to the emergence of adaptive behavioral responses to stress. However, despite growing evidence implicating the PVT in stress processing, the neural mechanisms by which stress impacts PVT neurocircuitry and promotes stressed states remain unknown. Here we show that stress exposure drives a rapid and persistent reduction of inhibitory transmission onto projection neurons o ...[more]