Ontology highlight
ABSTRACT:
SUBMITTER: Logan E
PROVIDER: S-EPMC6036805 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Logan Erin E Luabeya Angelique Kany Kany AKK Mulenga Humphrey H Mrdjen Dunja D Ontong Cynthia C Cunningham Adam F AF Tameris Michele M McShane Helen H Scriba Thomas J TJ Horsnell William G C WGC Hatherill Mark M
Frontiers in immunology 20180702
<h4>Background</h4>It is unclear whether antibodies can prevent <i>Mycobacterium tuberculosis</i> (<i>Mtb</i>) infection. In this study, we examined the relationship between total plasma IgG levels, IgG elicited by childhood vaccines and soil-transmitted helminths, and <i>Mtb</i> infection prevalence, defined by positive QuantiFERON (QFT) test.<h4>Methods</h4>We studied 100 <i>Mtb</i> uninfected infants, aged 4-6 months. Ten infants (10%) converted to positive QFT test (QFT+) within 2 years of f ...[more]