Ontology highlight
ABSTRACT:
SUBMITTER: Liutkeviciene R
PROVIDER: S-EPMC6037261 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Liutkevičienė Rasa R Vilkevičiūtė Alvita A Banevičus Mantas M Miežytė Raminta R Kriaučiūnienė Loresa L
Medicina (Kaunas, Lithuania) 20180507 2
<i>Background and objective:</i> Optic neuritis (ON) is characterized by painful, usually monocular vision loss with decreased visual acuity and defects of the visual field and color vision. The etiology and pathophysiology of ON is not completely clear. It is thought that a matrix metalloproteinase 2 (<i>MMP-2)</i> gene plays an essential role in this autoimmune inflammatory disease. The aim of this study was to determine the relationship between the <i>MMP-2 (-1306 C/T)</i> <i>rs243865</i> gen ...[more]