Erectile dysfunction is associated with subclinical carotid vascular disease in young men lacking widely-known risk factors.

ABSTRACT: This study aimed to gain insight into the underlying pathogenesis of erectile dysfunction in young men under the age of 40 years without widely-known risk factors. Compared with normal controls, patients with erectile dysfunction had increased carotid intima-media thickness, fasting levels of blood glucose and insulin, and homeostatic model assessment index, as well as lower flow-mediated vasodilation and testosterone levels (P < 0.05), though all of these values were within their respective normal range. Multivariate logistic regression analysis identified carotid intima-media thickness, flow-mediated vasodilation, insulin level, and homeostatic model assessment index as significant predictors of erectile dysfunction. Young men with flow-mediated vasodilation <10.65% were 11.645 times mor

SUBMITTER: Yao FJ 

PROVIDER: S-EPMC6038168 | biostudies-literature | 2018 Jul-Aug

REPOSITORIES: biostudies-literature