Registry Cohort Study to Determine Risk for Multiple Sclerosis after Vaccination for Pandemic Influenza A(H1N1) with Arepanrix, Manitoba, Canada.
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ABSTRACT:
SUBMITTER: Mahmud SM
PROVIDER: S-EPMC6038732 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
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Registry Cohort Study to Determine Risk for Multiple Sclerosis after Vaccination for Pandemic Influenza A(H1N1) with Arepanrix, Manitoba, Canada.
Mahmud Salaheddin M SM Bozat-Emre Songul S Mostaço-Guidolin Luiz C LC Marrie Ruth Ann RA
Emerging infectious diseases 20180701 7
To investigate a potential risk for multiple sclerosis (MS) after vaccination with Arepanrix, the GlaxoSmithKline AS03-adjuvanted influenza A(H1N1)pdm09 vaccine, we used the provincewide immunization registry for Manitoba, Canada, to match 341,347 persons vaccinated during the 2009 pandemic to 485,941 unvaccinated persons on age, sex, address, and a propensity score measuring the probability of vaccination. We used a previously validated algorithm to identify MS cases from provincial hospital, p ...[more]
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