Unknown

Dataset Information

0

Global Distribution of Human Protoparvoviruses.


ABSTRACT: Development of next-generation sequencing and metagenomics has revolutionized detection of novel viruses. Among these viruses are 3 human protoparvoviruses: bufavirus, tusavirus, and cutavirus. These viruses have been detected in feces of children with diarrhea. In addition, cutavirus has been detected in skin biopsy specimens of cutaneous T-cell lymphoma patients in France and in 1 melanoma patient in Denmark. We studied seroprevalences of IgG against bufavirus, tusavirus, and cutavirus in various populations (n = 840), and found a striking geographic difference in prevalence of bufavirus IgG. Although prevalence was low in adult populations in Finland (1.9%) and the United States (3.6%), bufavirus IgG was highly prevalent in populations in Iraq (84.8%), Iran (56.1%), and Kenya (72.3%). Conversely, cutavirus IgG showed evenly low prevalences (0%-5.6%) in all cohorts, and tusavirus IgG was not detected. These results provide new insights on the global distribution and endemic areas of protoparvoviruses.

SUBMITTER: Vaisanen E 

PROVIDER: S-EPMC6038761 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC5707561 | biostudies-literature
| S-EPMC5155296 | biostudies-literature
| PRJEB17632 | ENA
| S-EPMC1635517 | biostudies-other
| S-EPMC8026617 | biostudies-literature
| S-EPMC1891239 | biostudies-literature
| S-EPMC7354515 | biostudies-literature
| S-EPMC3371712 | biostudies-literature
2012-07-18 | E-ERAD-81 | biostudies-arrayexpress
| S-EPMC7335308 | biostudies-literature