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Outsmart HPV: Acceptability and short-term effects of a web-based HPV vaccination intervention for young adult gay and bisexual men.


ABSTRACT: BACKGROUND:Effective interventions to promote human papillomavirus (HPV) vaccination are needed, particularly among populations at increased risk of HPV-related disease. We developed and pilot tested a web-based intervention, Outsmart HPV, to promote HPV vaccination among young gay and bisexual men (YGBM). METHODS:In 2016, we recruited a national sample (n?=?150) of YGBM ages 18-25 in the United States who had not received any doses of HPV vaccine. Participants were randomized to receive either standard HPV vaccination information (control) or population-targeted, individually-tailored content (Outsmart HPV intervention). We assessed between group differences in HPV vaccination attitudes and beliefs immediately following the intervention using multiple linear regression. RESULTS:There were no differences in HPV vaccination attitudes, beliefs and intentions between groups at baseline. Compared to participants in the control group, intervention participants reported: greater perception that men who have sex with men are at higher risk for anal cancer relative to other men (b?=?0.34); greater HPV vaccination self-efficacy (b?=?0.15); and fewer perceived harms of HPV vaccine (b?=?-0.34) on posttest surveys (all p??4.4 on a 5-point scale). CONCLUSIONS:Findings from this study provide preliminary support for a brief, tailored web-based intervention in improving HPV vaccination attitudes and beliefs among YGBM. An important next step is to determine the effects of Outsmart HPV on HPV vaccine uptake. CLINICAL TRIALS REGISTRATION:ClinicalTrials.gov identifier NCT02835755.

SUBMITTER: McRee AL 

PROVIDER: S-EPMC6039283 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature

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