RutA-Catalyzed Oxidative Cleavage of the Uracil Amide Involves Formation of a Flavin-N5-oxide.
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ABSTRACT:
SUBMITTER: Adak S
PROVIDER: S-EPMC6040642 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
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RutA-Catalyzed Oxidative Cleavage of the Uracil Amide Involves Formation of a Flavin-N5-oxide.
Adak Sanjoy S Begley Tadhg P TP
Biochemistry 20170710 29
RutA is a novel flavoenzyme on the uracil catabolic pathway that catalyzes uracil ring opening by a unique amide oxidation reaction. Here we provide evidence that this reaction also involves the formation of a flavin-N5-oxide. ...[more]
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