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AnexVis: visual analytics framework for analysis of RNA expression.

ABSTRACT: Summary:Although RNA expression data are accumulating at a remarkable speed, gaining insights from them still requires laborious analyses, which hinder many biological and biomedical researchers. This report introduces a visual analytics framework that applies several well-known visualization techniques to leverage understanding of an RNA expression dataset. Our analyses on glycosaminoglycan-related genes have demonstrated the broad application of this tool, anexVis (analysis of RNA expression), to advance the understanding of tissue-specific glycosaminoglycan regulation and functions, and potentially other biological pathways. Availability and implementation:The application is accessible at https://anexvis.chpc.utah.edu/, source codes deposited on GitHub. Supplementary information:Supplementary data are available at Bioinformatics online.

SUBMITTER: Tran DT

PROVIDER: S-EPMC6041878 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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anexVis: visual analytics framework for analysis of RNA expression.

Tran Diem-Trang DT Zhang Tian T Stutsman Ryan R Might Matthew M Desai Umesh R UR Kuberan Balagurunathan B

Bioinformatics (Oxford, England) 20180701 14

<h4>Summary</h4>Although RNA expression data are accumulating at a remarkable speed, gaining insights from them still requires laborious analyses, which hinder many biological and biomedical researchers. This report introduces a visual analytics framework that applies several well-known visualization techniques to leverage understanding of an RNA expression dataset. Our analyses on glycosaminoglycan-related genes have demonstrated the broad application of this tool, anexVis (analysis of RNA expr ...[more]

PMID: 29506198

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