Ontology highlight
ABSTRACT:
SUBMITTER: Jaroentomeechai T
PROVIDER: S-EPMC6043479 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Jaroentomeechai Thapakorn T Stark Jessica C JC Natarajan Aravind A Glasscock Cameron J CJ Yates Laura E LE Hsu Karen J KJ Mrksich Milan M Jewett Michael C MC DeLisa Matthew P MP
Nature communications 20180712 1
The emerging discipline of bacterial glycoengineering has made it possible to produce designer glycans and glycoconjugates for use as vaccines and therapeutics. Unfortunately, cell-based production of homogeneous glycoproteins remains a significant challenge due to cell viability constraints and the inability to control glycosylation components at precise ratios in vivo. To address these challenges, we describe a novel cell-free glycoprotein synthesis (CFGpS) technology that seamlessly integrate ...[more]