Ontology highlight
ABSTRACT:
SUBMITTER: Perovic V
PROVIDER: S-EPMC6043496 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Perovic Vladimir V Sumonja Neven N Marsh Lindsey A LA Radovanovic Sandro S Vukicevic Milan M Roberts Stefan G E SGE Veljkovic Nevena N
Scientific reports 20180712 1
Intrinsically disordered proteins (IDPs) are characterized by the lack of a fixed tertiary structure and are involved in the regulation of key biological processes via binding to multiple protein partners. IDPs are malleable, adapting to structurally different partners, and this flexibility stems from features encoded in the primary structure. The assumption that universal sequence information will facilitate coverage of the sparse zones of the human interactome motivated us to explore the possi ...[more]