Ontology highlight
ABSTRACT:
SUBMITTER: Romeiro FG
PROVIDER: S-EPMC6044187 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
NeuroImage. Clinical 20180328
Branched-chain amino acids increase the brain perfusion of patients with hepatic encephalopathy (HE), but the amino acid and the mechanisms involved are still unknown. This study compared brain perfusion and clinical improvement during leucine or isoleucine supplementation. After randomization, 27 subjects with cirrhosis and HE received leucine or isoleucine supplements for one year. Brain single Photon Emission Computed Tomography (SPECT) and dynamic brain scintigraphy (DBS) were performed pret ...[more]