Unknown

Dataset Information

0

Singlet Oxygen Generation with Chemical Excitation of an Erythrosine-Luminol Conjugate.


ABSTRACT: Chemical generation of singlet oxygen under biologically relevant conditions is very important, considering the role played by singlet oxygen in cancer therapeutics. We now demonstrate that a luminol derivative can be chemically excited and transfer the excitation energy to the covalently attached photosensitizer derived from erythrosin. A photosensitizer module, when excited in this manner, can generate singlet oxygen in solution. As hydrogen peroxide is present in a relatively high concentration in cancer cells, singlet oxygen generation through chemical excitation may evolve into an important therapeutic approach.

SUBMITTER: Yesilgul N 

PROVIDER: S-EPMC6044502 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC4878812 | biostudies-literature
| S-EPMC5756573 | biostudies-literature
| S-EPMC6385666 | biostudies-literature
| S-EPMC4730142 | biostudies-literature
| S-EPMC4532730 | biostudies-literature
| S-EPMC3279295 | biostudies-literature
| S-EPMC7891382 | biostudies-literature
| S-EPMC5634745 | biostudies-literature
| S-EPMC3164884 | biostudies-literature
| S-EPMC7327044 | biostudies-literature