Ontology highlight
ABSTRACT:
SUBMITTER: Bhatnagar S
PROVIDER: S-EPMC6044761 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
ACS omega 20170406 4
Transcutaneous antigen administration provides an alternative to invasive syringe injections. The objective of this study was to investigate the feasibility of fabrication and antigen delivery using microneedles made from corn protein, zein. Micromolding technique was used to cast cone-shaped zein microneedles (ZMNs). The insertion of ZMNs and the delivery of the model antigen, ovalbumin (OVA), into the skin was confirmed by histological examination and confocal microscopy. In addition, a signif ...[more]