Ontology highlight
ABSTRACT:
SUBMITTER: Tadokoro Y
PROVIDER: S-EPMC6044787 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Tadokoro Yohei Y Nishikawa Teruaki T Ichimori Taichi T Matsunaga Satoko S Fujita Masaki J MJ Sakai Ryuichi R
ACS omega 20170321 3
New brominated β-carbolines irenecarbolines A (<b>1</b>) and B (<b>4</b>) along with known β-carbolines <b>2</b> and <b>3</b> and a new 8-oxoisoguanine derivative, <b>5</b>, were isolated from a solitary ascidian, <i>Cnemidocarpa irene</i>. The structures of these compounds were determined on the basis of their spectral data. All, except for <b>3</b>, inhibited the action of acetylcholinesterase (AchE). The activities of <b>1</b> and <b>5</b> were comparable to those of galantamine, a clinically ...[more]