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Ultrafine Highly Magnetic Fluorescent ?-Fe2O3/NCD Nanocomposites for Neuronal Manipulations.


ABSTRACT: In this work, we describe a low-cost, two-step synthesis of composites of nitrogen-doped carbon quantum dots (NCDs) with ?-Fe2O3 (NCDs/?-Fe2O3), which is based on a hydrothermal cum co-precipitation method. The product is a fine powder of particles having an average diameter of 9 ± 3 nm. The physical and chemical properties of NCDs/?-Fe2O3 were studied, as well as the superconducting quantum interference device and Mossbauer analysis of the magnetic properties of these nanocomposites. The interaction of NCDs/?-Fe2O3 nanocomposites with neuron-like cells was examined, showing efficient uptake and low toxicity. Our research demonstrates the use of the nanocomposites for imaging and for controlling the cellular motility. The NCDs/?-Fe2O3 nanocomposites are promising because of their biocompatibility, photostability, and potential selective affinity, paving the way for multifunctional biomedical applications.

SUBMITTER: Kumar VB 

PROVIDER: S-EPMC6045473 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature

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Ultrafine Highly Magnetic Fluorescent γ-Fe<sub>2</sub>O<sub>3</sub>/NCD Nanocomposites for Neuronal Manipulations.

Kumar Vijay Bhooshan VB   Marcus Michal M   Porat Ze'ev Z   Shani Lior L   Yeshurun Yosef Y   Felner Israel I   Shefi Orit O   Gedanken Aharon A  

ACS omega 20180213 2


In this work, we describe a low-cost, two-step synthesis of composites of nitrogen-doped carbon quantum dots (NCDs) with γ-Fe<sub>2</sub>O<sub>3</sub> (NCDs/γ-Fe<sub>2</sub>O<sub>3</sub>), which is based on a hydrothermal cum co-precipitation method. The product is a fine powder of particles having an average diameter of 9 ± 3 nm. The physical and chemical properties of NCDs/γ-Fe<sub>2</sub>O<sub>3</sub> were studied, as well as the superconducting quantum interference device and Mossbauer analy  ...[more]

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