Ontology highlight
ABSTRACT:
SUBMITTER: Santos MR
PROVIDER: S-EPMC6045739 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
RMD open 20180628 1
<h4>Objectives</h4>Ankylosing spondylitis (AS) is the most prevalent form of spondyloarthritis, with a known genetic association with the HLA-B27 molecule. The aim of this study was to assess the contribution of the HLA-G, HLA-E and HLA-F to AS susceptibility/protection in Portuguese patients with HLA-B27 AS and HLA-B27 unaffected controls.<h4>Methods</h4>High-resolution typing of <i>HLA-G</i>, <i>HLA-E</i> and <i>HLA-F</i> was performed in 228 patients with HLA-B27 AS and 244 HLA-B27 unaffected ...[more]