Ontology highlight
ABSTRACT:
SUBMITTER: Xia Z
PROVIDER: S-EPMC6046250 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Xia Zhangyong Z Gu Mingliang M Jia Xiaodong X Wang Xiaoting X Wu Chunxia C Guo Jiangwen J Zhang Liyong L Du Yifeng Y Wang Jiyue J
Aging 20180601 6
Atherosclerosis (AS) is a multifactorial disease. Exploration of DNA methylation in regulating gene transcription in a cell type- and stage-specific manner will shed light on understanding the biological processes associated with plaque stability. We identified 174 up-regulated genes with hypo-methylation in the promoter, and 86 down-regulated genes with hyper-methylation in the promoter, in AS vs. healthy controls. Among them, high expression of signaling lymphocytic activation molecule 7 (SLAM ...[more]