Ontology highlight
ABSTRACT:
SUBMITTER: Zhang R
PROVIDER: S-EPMC6047024 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
ACS medicinal chemistry letters 20180507 7
Recent visible-light photoredox catalyzed C(sp<sup>3</sup>)-C(sp<sup>2</sup>) cross-coupling provides a novel transformation to potentially enable the synthesis of medicinal chemistry targets. Here, we report a profiling study of photocatalytic C(sp<sup>3</sup>)-C(sp<sup>2</sup>) cross-coupling, both decarboxylative coupling and cross-electrophile coupling, with 18 pharmaceutically relevant aryl halides by using either Kessil lamp or our newly developed integrated photoreactor. Integrated photor ...[more]