Ontology highlight
ABSTRACT:
SUBMITTER: Hibar DP
PROVIDER: S-EPMC6053271 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Hibar Derrek P DP Cheung Joshua W JW Medland Sarah E SE Mufford Mary S MS Jahanshad Neda N Dalvie Shareefa S Ramesar Raj R Stewart Evelyn E van den Heuvel Odile A OA Pauls David L DL Knowles James A JA Stein Dan J DJ Thompson Paul M PM
The British journal of psychiatry : the journal of mental science 20180701 1
<h4>Background</h4>Many studies have identified changes in the brain associated with obsessive-compulsive disorder (OCD), but few have examined the relationship between genetic determinants of OCD and brain variation.AimsWe present the first genome-wide investigation of overlapping genetic risk for OCD and genetic influences on subcortical brain structures.<h4>Method</h4>Using single nucleotide polymorphism effect concordance analysis, we measured genetic overlap between the first genome-wide as ...[more]