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Use of a web-based app to improve breast cancer symptom management and adherence for aromatase inhibitors: a randomized controlled feasibility trial.


ABSTRACT: PURPOSE:For postmenopausal women with hormone receptor-positive breast cancer, long-term use of aromatase inhibitors (AIs) significantly reduces the risk of cancer recurrence and improves survival. Still, many patients are nonadherent due to adverse side effects. We conducted a pilot randomized controlled trial to test the use of a web-based application (app) designed with and without weekly reminders for patients to report real-time symptoms and AI use outside of clinic visits with built-in alerts to patients' oncology providers. Our goal was to improve symptom burden and medication adherence. METHODS:Forty-four women with early-stage breast cancer and a new AI prescription were randomized to either an App+Reminder (weekly reminders to use app) or an App (no reminders) group. Pre- and post-assessment data were collected from all participants. RESULTS:Participants in the App+Reminder group had higher weekly app usage rate (74 vs. 38%, p?

SUBMITTER: Graetz I 

PROVIDER: S-EPMC6054536 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature

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Use of a web-based app to improve breast cancer symptom management and adherence for aromatase inhibitors: a randomized controlled feasibility trial.

Graetz Ilana I   McKillop Caitlin N CN   Stepanski Edward E   Vidal Gregory A GA   Anderson Janeane N JN   Schwartzberg Lee S LS  

Journal of cancer survivorship : research and practice 20180228 4


<h4>Purpose</h4>For postmenopausal women with hormone receptor-positive breast cancer, long-term use of aromatase inhibitors (AIs) significantly reduces the risk of cancer recurrence and improves survival. Still, many patients are nonadherent due to adverse side effects. We conducted a pilot randomized controlled trial to test the use of a web-based application (app) designed with and without weekly reminders for patients to report real-time symptoms and AI use outside of clinic visits with buil  ...[more]

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