Ontology highlight
ABSTRACT:
SUBMITTER: Ollivier N
PROVIDER: S-EPMC6054628 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Ollivier Nathalie N Toupy Thomas T Hartkoorn Ruben C RC Desmet Rémi R Monbaliu Jean-Christophe M JM Melnyk Oleg O
Nature communications 20180720 1
Cyclic peptide-based therapeutics have a promising growth forecast that justifies the development of microfluidic systems dedicated to their production, in phase with the actual transitioning toward continuous flow and microfluidic technologies for pharmaceutical production. The application of the most popular method for peptide cyclization in water, i.e., native chemical ligation, under microfluidic conditions is still unexplored. Herein, we report a general strategy for fast and efficient pept ...[more]