Ontology highlight
ABSTRACT:
SUBMITTER: Clarke DE
PROVIDER: S-EPMC6055752 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Clarke David E DE Parmenter Christopher D J CDJ Scherman Oren A OA
Angewandte Chemie (International ed. in English) 20180517 26
Oligopeptide-based supramolecular hydrogels hold promise in a range of applications. The gelation of these systems is hard to control, with minor alterations in the peptide sequence significantly influencing the self-assembly process. We explored three pentapeptide sequences with different charge distributions and discovered that they formed robust, pH-responsive hydrogels. By altering the concentration and charge distribution of the peptide sequence, the stiffness of the hydrogels could be tune ...[more]