Progress in the treatment of solid tumors with apatinib: a systematic review.
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SUBMITTER: Zhao D
PROVIDER: S-EPMC6056166 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
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Progress in the treatment of solid tumors with apatinib: a systematic review.
Zhao Deze D Hou Helei H Zhang Xiaochun X
OncoTargets and therapy 20180719
With the investigation of molecular targets, many agents, such as trastuzumab and ramucirumab, have attained a positive outcome in oncotherapy. Vascular endothelial growth factor (VEGF) is considered a potent factor in angiogenesis and plays an important role in the growth of tumors. Moreover, both VEGF and its receptor are usually excessively expressed in solid tumors and could be hopeful targets for the treatment of neoplasms. Apatinib (YN968D1) is an oral small-molecule tyrosine kinase inhibi ...[more]
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